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Which of the following reactions is catalyzed by glutamate dehydrogenase catalyze?


A) the reductive amination of a-ketoglutarate to yield glutamate
B) phosphorylation of carbamate to yield carbamoyl phosphate
C) the amidation of the g-carboxyl group of glutamate to form glutamine
D) the deadenylation of glutamine synthetase

E) All of the above
F) B) and C)

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Which of the following compounds is an intermediate in biosynthesis of ornithine and a regulator of carbamoyl-phosphate synthetase-I?


A) γ-glutamyl-phosphate
B) α-ketoglutarate
C) N-acetylglutamate
D) glutamine-5-phosphate

E) B) and C)
F) A) and C)

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Which of the following is NOT a part of the degradation pathway of valine,isoleucine,and methionine leading to succinyl-CoA?


A) biotin and ATP
B) acetyl-CoA
C) methylmalonyl-CoA
D) propionyl-CoA

E) None of the above
F) B) and C)

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Which of the following enzymes catalyzes the reaction below? N₂ + 10 H⁺+ 8 e⁻ → 2 NH₄⁺ + H₂


A) nitrate reductase
B) nitrogenase
C) glutamate dehydrogenase
D) glutamate synthase

E) All of the above
F) B) and C)

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Which of the following molecules is synthesized and then transaminated using glutamate,for subsequent use in amino acid biosynthesis in plants and microorganisms?


A) an a-keto acid
B) an acetyl-CoA derivative
C) a phospho-carbon skeleton
D) a nitrogenous base

E) A) and C)
F) None of the above

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Which of the following products is formed from the glutamate synthase-catalyzed reaction?


A) glutamate
B) a-ketoglutarate
C) NADPH
D) N-acetylglutamate

E) A) and D)
F) B) and C)

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Which of the following outcomes would be a result of a high [Gln]/[α-KG] ratio?


A) a need for ammonium fixation by glutamine synthetase
B) an increase in activity of glutamine synthetase
C) an increase in the degree of adenylation of glutamine synthetase
D) inhibition of AT:PIIA and stimulation of AT:PIID

E) A) and D)
F) A) and C)

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